Neuroprotective, neurotherapeutic, and neurometabolic effects of carbon monoxide
نویسندگان
چکیده
منابع مشابه
Neuroprotective, neurotherapeutic, and neurometabolic effects of carbon monoxide
Studies in animal models show that the primary mechanism by which heme-oxygenases impart beneficial effects is due to the gaseous molecule carbon monoxide (CO). Produced in humans mainly by the catabolism of heme by heme-oxygenase, CO is a neurotransmitter important for multiple neurologic functions and affects several intracellular pathways as a regulatory molecule. Exogenous administration of...
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MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...
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The purpose of this study was to determine whether low doses of carbon monoxide (CO) exacerbate myocardial ischemia during a progressive exercise test. The effect of CO exposure was evaluated using the objective measure of time to development of electrocardiographic changes indicative of ischemia and the subjective measure of time to onset of angina. Sixty-three male subjects (41-75 years) with...
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Cigarette smoking causes injury of coronary arteries as well as other arteries. Sudden death is more frequent in heavy smokers than in non smokers. Studies showed that dangerous arrhythmias will be the result of effect of nicotine when injected in the animals. Carbon-monooxide is also dangerous for man when it is produced by smoking. The prevention of heart disease will be more satisfactory ...
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In this research, a mineral barite powder was reduced by carbon monoxide gas and the effects of reduction time and temperature was investigated as well as barite particle size. Results showed that the best result would be feasible when the barite particle sizes are between (-70 +100) in mesh scale. The barite reduction could reach the maximum level (98%) after reduction by carbon monoxide at 85...
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ژورنال
عنوان ژورنال: Medical Gas Research
سال: 2012
ISSN: 2045-9912
DOI: 10.1186/2045-9912-2-32